RASSF1A in maternal plasma as a molecular marker of preeclampsia.

  title={RASSF1A in maternal plasma as a molecular marker of preeclampsia.},
  author={Nikolas Papantoniou and Vassilis Bagiokos and Kostantinos Agiannitopoulos and Aggeliki Kolialexi and Aspasia Destouni and Georgia Tounta and Emmanuel Kanavakis and Aris Antsaklis and Ariadni Mavrou},
  journal={Prenatal diagnosis},
  volume={33 7},
OBJECTIVES This study aimed to quantitate cell free (cf) and cell free fetal (cff) DNA in maternal plasma by determining RASSF1A levels before and after enzyme digestion in women who subsequently developed preeclampsia (PE) and compare them with uncomplicated pregnancies. METHODS Twenty-four samples from pregnant women who developed PE and 48 samples from women with uncomplicated pregnancies were analysed. Blood samples were obtained at 11-13 weeks. cfDNA was determined by quantifying RASSF1A… CONTINUE READING

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Fetal-specific hypermethylated RASSF1A quantification in pregnancy.

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians • 2017
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