RAS diseases in children.


RAS genes encode a family of 21 kDa proteins that are an essential hub for a number of survival, proliferation, differentiation and senescence pathways. Signaling of the RAS-GTPases through the RAF-MEK-ERK pathway, the first identified mitogen-associated protein kinase (MAPK) cascade is essential in development. A group of genetic syndromes, named… (More)
DOI: 10.3324/haematol.2014.114595


Cite this paper

@article{Niemeyer2014RASDI, title={RAS diseases in children.}, author={Charlotte Marie Niemeyer}, journal={Haematologica}, year={2014}, volume={99 11}, pages={1653-62} }