RAIDD is a new 'death' adaptor molecule

@article{Duan1997RAIDDIA,
  title={RAIDD is a new 'death' adaptor molecule},
  author={Hangjun Duan and Vishva M. Dixit},
  journal={Nature},
  year={1997},
  volume={385},
  pages={86-89}
}
THE effector arm of the cell-death pathway is composed of cysteine proteases belonging to the ICE/CED-3 family1,2. In metazoan cells these exist as inactive polypeptide precursors (zymogens), each composed of a prodomain, which is cleaved to activate the protease, and a large and small catalytic subunit. The coupling of these 'death' proteases to signalling pathways is probably mediated by adaptor molecules that contain protein–protein interaction motifs such as the death domain1. Here we… 

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