RAGE influences obesity in mice

  title={RAGE influences obesity in mice},
  author={Beatrice Leuner and Martin Max and Kristina Thamm and C. Kausler and Yuliana Yakobus and Angelika Bierhaus and Saadettin Sel and Britt Hofmann and R. Silber and Andreas Simm and Dr. N. Nass},
  journal={Zeitschrift f{\"u}r Gerontologie und Geriatrie},
The metabolic syndrome is defined by the presence of obesity, insulin resistance, dyslipidemia, and hypertension. Advanced glycation end products (AGEs) are stable end products of the Maillard reaction, whereby AGE accumulation is considered not only a biomarker of aging but is also associated with several degenerative diseases. AGEs are recognized by several receptor molecules of which the receptor of AGEs (RAGE) is currently the most intensively studied receptor. Activation of RAGE causes an… CONTINUE READING
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