RAD51-dependent break-induced replication in yeast.

@article{Davis2004RAD51dependentBR,
  title={RAD51-dependent break-induced replication in yeast.},
  author={Allison Pitinii Davis and Lorraine S Symington},
  journal={Molecular and cellular biology},
  year={2004},
  volume={24 6},
  pages={
          2344-51
        }
}
A chromosome fragmentation assay was used to measure the efficiency and genetic control of break-induced replication (BIR) in Saccharomyces cerevisiae. Formation of a chromosome fragment by de novo telomere generation at one end of the linear vector and recombination-dependent replication of 100 kb of chromosomal sequences at the other end of the vector occurred at high frequency in wild-type strains. RAD51 was required for more than 95% of BIR events involving a single-end invasion and was… CONTINUE READING

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Break-induced replication: a review and an example in budding yeast.

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