RAD51 135G>C polymorphism and breast cancer risk: a meta-analysis

  title={RAD51 135G>C polymorphism and breast cancer risk: a meta-analysis},
  author={Guo-Wu Zhou and Jia Hu and Xu-Dong Peng and Qiang Hua Li},
  journal={Breast Cancer Research and Treatment},
Mutations in RAD51 gene are believed to be associated with elevated breast cancer risk. However, several case–control studies focusing on the association between RAD51 135G>C and breast cancer risk failed to achieve consensus. To clarify the effect of RAD51 135G>C polymorphism on breast cancer, a meta-analysis was performed. By searching PubMed and EMBASE, a total of 14 case–control studies, containing 12,183 cases and 10,183 controls, were included. The strength of association between RAD51… CONTINUE READING


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IHCC-Breast Cancer Study Group (2009) Do BRCA1 modifiers also affect the risk of breast cancer

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