RAD51 135G/C polymorphism and breast cancer risk: a meta-analysis from 21 studies

@article{Gao2010RAD511P,
  title={RAD51 135G/C polymorphism and breast cancer risk: a meta-analysis from 21 studies},
  author={Lin-bo Gao and Xin-min Pan and Lijuan Li and Wei-bo Liang and Yi Zhu and Lu-shun Zhang and Yonggang Wei and Ming Tang and Lin Zhang},
  journal={Breast Cancer Research and Treatment},
  year={2010},
  volume={125},
  pages={827-835}
}
Growing evidence suggests that RAD51 plays a pivotal role in the repair of DNA double-strand breaks and the maintenance of genomic stability. A single nucleotide polymorphism, 135G/C, has been identified in the 5′ untranslated region of the RAD51 gene and has been shown to influence gene transcription activity. Previous studies yielded conflicting results as to the association of 135G/C polymorphism with breast cancer. We aimed to assess the effect of 135G/C of RAD51 on breast cancer… CONTINUE READING

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Do BRCA 1 modifiers also affect the risk of breast cancer in noncarriers ?

  • A Jakubowska, K Jaworska, M Lener, SA Narod, J Lubinski
  • Eur J Cancer
  • 2009

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