RAD in de novo renal transplantation: comparison of three doses on the incidence and severity of acute rejection.

@article{Kahan2001RADID,
  title={RAD in de novo renal transplantation: comparison of three doses on the incidence and severity of acute rejection.},
  author={Barry D. Kahan and Bruce Kaplan and Marc I. Lorber and Michael Bjorn Winkler and Nathalie Cambon and R S Boger},
  journal={Transplantation},
  year={2001},
  volume={71 10},
  pages={1400-6}
}
BACKGROUND The effects of three doses of RAD (40-O-[2-hydroxyethyl]-rapamycin), a novel macrolide with potent immunosuppressive and antiproliferative properties, on the incidence and severity of acute rejection episodes as well as its tolerability were evaluated in a dose-ranging study in de novo renal transplant recipients. METHODS In this double-blind, parallel group, multicenter study, recipients were randomized to receive 1 mg, 2 mg, or 4 mg/day of RAD in combination with Neoral… CONTINUE READING

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