RACK1 is involved in β-amyloid impairment of muscarinic regulation of GABAergic transmission.

@article{Liu2011RACK1II,
  title={RACK1 is involved in β-amyloid impairment of muscarinic regulation of GABAergic transmission.},
  author={Wenhua Liu and Fei Dou and Jian Feng and Zhen Yan},
  journal={Neurobiology of aging},
  year={2011},
  volume={32 10},
  pages={1818-26}
}
RACK1 (receptor for activated C-kinase 1), an anchoring protein that shuttles activated PKC to cellular membranes, plays an important role in PKC-mediated signal transduction pathways. A significant loss of RACK1 has been found in the brain of aging animals and Alzheimer's disease (AD) patients, which implicates the potential involvement of RACK1 in altered… CONTINUE READING