RAC protein induces enzymatic access to the maturing 3'-end of the 25S rRNA in Schizosaccharomyces pombe.

Abstract

In Schizosaccharomyces pombe, interdependency between steps in the processing of the rRNAs is mediated by a large protein complex (RAC) which interacts with the non-conserved transcribed spacers. The RAC complex exhibits no nuclease activity but dramatically alters the efficiency and specificity of Pac1 nuclease cleavage, leading to the removal of the 3… (More)
DOI: 10.1016/j.bbrc.2008.01.068

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