RABL2 Is Required for Hepatic Fatty Acid Homeostasis and Its Dysfunction Leads to Steatosis and a Diabetes-Like State.

@article{Lo2016RABL2IR,
  title={RABL2 Is Required for Hepatic Fatty Acid Homeostasis and Its Dysfunction Leads to Steatosis and a Diabetes-Like State.},
  author={Jennifer Chi Yi Lo and Anne E. O'Connor and Zane B Andrews and Camden Y. Lo and Tony Tiganis and Matthew J Watt and Moira K O'Bryan},
  journal={Endocrinology},
  year={2016},
  volume={157 12},
  pages={
          4732-4743
        }
}
Fatty liver, or hepatic steatosis, is an alarmingly common pathology in western societies, in large part because if left unheeded, it can lead to life-threatening forms of nonalcoholic fatty liver disease, including nonalcoholic steatohepatitis, fibrosis, cirrhosis, and hepatocellular carcinoma. As such, it is essential that we attain a greater understanding of the pathways that control energy partitioning in the liver and ultimately how they are impacted by environmental factors. Here, we… CONTINUE READING
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