R-twist gene expression during rat palatogenesis.

  title={R-twist gene expression during rat palatogenesis.},
  author={Agn{\`e}s Bloch-Zupan and Nora Hunter and Amanda Manthey and Jonathan Gibbins},
  journal={The International journal of developmental biology},
  volume={45 2},
Palatal clefting is often associated with premature fusion of cranial sutures in human craniosynostosis syndromes, many of which are characterised by mutations affecting the fibroblast growth factor receptor (FGFR) gene family. In palatal fusion, epithelio-mesenchymal transition (EMT) contributes to the dispersion of the midline epithelial seam. EMT has also been observed in neoplastic epithelial cells in relation to the acquisition of malignant characteristics where morphological changes are… CONTINUE READING


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