R region sequences in the long terminal repeat of a murine retrovirus specifically increase expression of unspliced RNAs.

@article{Trubetskoy1999RRS,
  title={R region sequences in the long terminal repeat of a murine retrovirus specifically increase expression of unspliced RNAs.},
  author={Alla M. Trubetskoy and Sharon A. Okenquist and Jack Lenz},
  journal={Journal of virology},
  year={1999},
  volume={73 4},
  pages={3477-83}
}
A stem-loop structure at the 5' end of the R region of the long terminal repeat (LTR) of the murine leukemia virus SL3 and other type C mammalian retroviruses is important for maximum levels of expression of a reporter gene under the control of the viral LTR. This element, termed the R region stem-loop (RSL), has a small effect on transcriptional initiation and no effect on RNA polymerase processivity. Its major effect is on posttranscriptional processing of LTR-driven transcripts. Here we… CONTINUE READING