R-Ras C-terminal sequences are sufficient to confer R-Ras specificity toH-Ras

@article{Hansen2002RRasCS,
  title={R-Ras C-terminal sequences are sufficient to confer R-Ras specificity toH-Ras},
  author={Malene Hansen and Elena V. Rusyn and Paul E. Hughes and Mark H Ginsberg and Adrienne D. Cox and Berthe Marie Willumsen},
  journal={Oncogene},
  year={2002},
  volume={21},
  pages={4448-4461}
}
Activated versions of the similar GTPases, H-Ras and R-Ras, have differing effects on biological phenotypes: Activated H-Ras strongly transforms many fibroblast cell lines causing dramatic changes in cell shape and cytoskeletal organization. In contrast, R-Ras transforms fewer cell lines and the transformed cells display only some of the morphological changes associated with H-Ras transformation. H-Ras cells can survive in the absence of serum whereas R-Ras cells seem to die by an apoptotic… CONTINUE READING
9 Citations
9 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations

References

Publications referenced by this paper.
Showing 1-9 of 9 references

Nat

  • IA Prior, A Harding, J Yan, J Sluimer, RG Parton, JF. Hancock
  • Cell. Biol., 3, 368 ± 375.
  • 2001
Highly Influential
14 Excerpts

Curr

  • BM Marte, P Rodriguez-Viciana, S Wennstrom, PH Warne, J. Downward
  • Biol., 7, 63 ± 70.
  • 1996
Highly Influential
4 Excerpts

Mol

  • D Woods, H Cherwinski, +6 authors M. McMahon
  • Cell. Biol., 21, 3192 ± 3205.
  • 2001

Proc

  • JX Zou, B Wang, MS Kalo, AH Zisch, EB Pasquale, E. Ruoslahti
  • Natl. Acad. Sci. USA, 96, 13813 ± 13818. Oncogene
  • 1999

Adv

  • R Khosravi-Far, S Campbell, KL Rossman, CJ. Der
  • Cancer Res., 72, 57 ± 107.
  • 1998
1 Excerpt

Br

  • Wyllie AH.
  • Med. Bull., 53, 451 ± 465.
  • 1997

Naunyn Schmiedebergs Arch

  • CC Chou, Yung BY.
  • Pharmacol., 355, 177 ± 182.
  • 1997

J

  • MA White, T Vale, JH Camonis, E Schafer, MH. Wigler
  • Biol. Chem., 271, 16439 ± 16442.
  • 1996

Ann

  • MA Schwartz, MD Schaller, MH. Ginsberg
  • Rev. Cell Dev. Biol., 11, 549 ± 599.
  • 1995

Similar Papers

Loading similar papers…