R-Gada: a fast and flexible pipeline for copy number analysis in association studies

  title={R-Gada: a fast and flexible pipeline for copy number analysis in association studies},
  author={Roger Pique-Regi and Alejandro C{\'a}ceres and Juan R. Gonz{\'a}lez},
  booktitle={BMC Bioinformatics},
Genome-wide association studies (GWAS) using Copy Number Variation (CNV) are becoming a central focus of genetic research. CNVs have successfully provided target genome regions for some disease conditions where simple genetic variation (i.e., SNPs) has previously failed to provide a clear association. Here we present a new R package, that integrates: (i) data import from most common formats of Affymetrix, Illumina and aCGH arrays; (ii) a fast and accurate segmentation algorithm to call CNVs… CONTINUE READING
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