Quorum sensing inhibitory potential and molecular docking studies of sesquiterpene lactones from Vernonia blumeoides.

@article{Aliyu2016QuorumSI,
  title={Quorum sensing inhibitory potential and molecular docking studies of sesquiterpene lactones from Vernonia blumeoides.},
  author={A. Aliyu and N. Koorbanally and B. Moodley and P. Singh and H. Chenia},
  journal={Phytochemistry},
  year={2016},
  volume={126},
  pages={
          23-33
        }
}
  • A. Aliyu, N. Koorbanally, +2 authors H. Chenia
  • Published 2016
  • Biology, Medicine
  • Phytochemistry
  • The increasing incidence of multidrug-resistant Gram-negative bacterial pathogens has focused research on the suppression of bacterial virulence via quorum sensing inhibition strategies, rather than the conventional antimicrobial approach. The anti-virulence potential of eudesmanolide sesquiterpene lactones previously isolated from Vernonia blumeoides was assessed by inhibition of quorum sensing and in silico molecular docking. Inhibition of quorum sensing-controlled violacein production in… CONTINUE READING
    15 Citations
    Anti-quorum sensing activity of Forsythia suspense extract against Chromobacterium violaceum by targeting CviR receptor
    • X. Zhuang, A. Zhang, Weihua Chu
    • Chemistry, Medicine
    • International microbiology : the official journal of the Spanish Society for Microbiology
    • 2019
    • 1
    Anti-biofilm activity of plant derived extracts against infectious pathogen-Pseudomonas aeruginosa PAO1.
    • 1
    Medicinal plant products targeting quorum sensing for combating bacterial infections.
    • 45

    References

    SHOWING 1-10 OF 39 REFERENCES
    Anti-Quorum Sensing Potential of Crude Kigelia africana Fruit Extracts
    • H. Chenia
    • Biology, Computer Science
    • Sensors
    • 2013
    • 58
    • PDF
    Inhibition of quorum sensing in Pseudomonas aeruginosa by sesquiterpene lactones.
    • 51
    Antiquorum sensing and antibiofilm potential of Capparis spinosa.
    • 125
    • Highly Influential
    Dietary phytochemicals as quorum sensing inhibitors.
    • 283
    • Highly Influential
    Effects of plant lactones on the production of biofilm of Pseudomonas aeruginosa.
    • 35
    • PDF
    In silico investigation of lactone and thiolactone inhibitors in bacterial quorum sensing using molecular modeling
    • 12
    • Highly Influential
    • PDF
    A simple screening protocol for the identification of quorum signal antagonists.
    • 254