Quo vadis multiple sclerosis?

  title={Quo vadis multiple sclerosis?},
  author={Israel Steiner and Ronit Mosberg-Galili},
Multiple sclerosis (MS) is a disease that currently defies attempts to provide meaningful therapy. Four major issues still elude the neurological community (Steiner and Wirguin 2000): (1) Is it a disease or are we grouping together various disease entities, hence is it a syndrome? (2) What should be the diagnostic criteria of MS? The current ones enable recruiting into clinical trials an extremely heterogeneous population of patients associated with a too significant biological noise to enable… CONTINUE READING