Quisqualate induces an inward current via mGluR activation in neocortical pyramidal neurons

@article{Chu2000QuisqualateIA,
  title={Quisqualate induces an inward current via mGluR activation in neocortical pyramidal neurons},
  author={Zhiguo Chu and John J Hablitz},
  journal={Brain Research},
  year={2000},
  volume={879},
  pages={88-92}
}
Activation of metabotropic glutamate receptors (mGluRs) has multiple effects on the excitability of pyramidal neurons in rat frontal neocortex. Synaptic transmission and intrinsic excitability are both affected. During studies of the effects of quisqualate on synaptic activity, it was observed that quisqualate also induced a slow inward current. Whole-cell patch clamp recordings were obtained from layer II/III pyramidal neurons of neocortical slices in vitro. The bath solution contained APV… Expand
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