Quinolones in treatment of human brucellosis: comparative trial of ofloxacin-rifampin versus doxycycline-rifampin.

@article{Akova1993QuinolonesIT,
  title={Quinolones in treatment of human brucellosis: comparative trial of ofloxacin-rifampin versus doxycycline-rifampin.},
  author={Murat Akova and Omrum Uzun and H Erdal Akalin and Mutlu Hayran and Serhat Unal and Deniz G{\"u}r},
  journal={Antimicrobial agents and chemotherapy},
  year={1993},
  volume={37 9},
  pages={1831-4}
}
Quinolones have been reported to be active against Brucella species in vitro. In this prospective randomized study, the efficacy and safety of the combination of ofloxacin plus rifampin were compared with the efficacy and safety of doxycycline plus rifampin, both combinations administered for a 6-week period in treatment of brucellosis. Sixty-one patients were enrolled in the study, and 49 had blood or bone marrow cultures positive for Brucella melitensis. Thirty patients received 200 mg of… CONTINUE READING

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BrucellosisMay be treated byRifampin
In this prospective randomized study , the efficacy and safety of the combination of ofloxacin plus rifampin were compared with the efficacy and safety of doxycycline plus rifampin , both combinations administered for a 6-week period in treatment of brucellosis .
In this prospective randomized study , the efficacy and safety of the combination of ofloxacin plus rifampin were compared with the efficacy and safety of doxycycline plus rifampin , both combinations administered for a 6-week period in treatment of brucellosis .
Quinolones in treatment of human brucellosis : comparative trial of ofloxacin - rifampin versus doxycycline - rifampin .
Quinolones in treatment of human brucellosis : comparative trial of ofloxacin - rifampin versus doxycycline - rifampin .
QuinolonesChemical structure ofOfloxacin
Quinolones in treatment of human brucellosis : comparative trial of ofloxacin - rifampin versus doxycycline - rifampin .
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