Quinolone resistance-determining region mutations and por type of Neisseria gonorrhoeae isolates: resistance surveillance and typing by molecular methodologies.

@article{Giles2004QuinoloneRR,
  title={Quinolone resistance-determining region mutations and por type of Neisseria gonorrhoeae isolates: resistance surveillance and typing by molecular methodologies.},
  author={Julie A Giles and Jason R Falconio and Jeffrey D Yuenger and Jonathan M. Zenilman and Michael Dan and Margaret C. Bash},
  journal={The Journal of infectious diseases},
  year={2004},
  volume={189 11},
  pages={2085-93}
}
Quinolone resistance is increasing rapidly in Neisseria gonorrhoeae and is a significant public health problem that requires ongoing surveillance. To examine the feasibility of molecular surveillance of quinolone resistance, and to further characterize an outbreak of resistant N. gonorrhoeae in Israel, the quinolone resistance-determining region (QRDR) sequences and the por types of 80 N. gonorrhoeae isolates were determined using molecular techniques. QRDRs of gyrA and parC were amplified by… CONTINUE READING

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