Quinine-induced hemolytic-uremic syndrome.

@article{Crum2000QuinineinducedHS,
  title={Quinine-induced hemolytic-uremic syndrome.},
  author={Nancy F. Crum and Preston Gable},
  journal={Southern medical journal},
  year={2000},
  volume={93 7},
  pages={
          726-8
        }
}
Quinine is still frequently used by practitioners for the treatment of nocturnal leg cramps, despite the lack of Food and Drug Administration (FDA) approval. We report the 15th case of quinine-induced hemolytic-uremic syndrome (HUS) in the medical literature. The likely mechanism by which quinine induces HUS is via quinine-dependent antibodies to blood cellular constituents. These antibodies likely cause endothelial damage and the resultant nephropathy, microangiopathic hemolytic anemia, and… CONTINUE READING

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