Quince peel polyphenolic extract blocks human colon adenocarcinoma LS174 cell growth and potentiates 5-fluorouracil efficacy

@inproceedings{RiahiChebbi2015QuincePP,
  title={Quince peel polyphenolic extract blocks human colon adenocarcinoma LS174 cell growth and potentiates 5-fluorouracil efficacy},
  author={Ichrak Riahi-Chebbi and Meriam Haoues and Makram Essafi and Ons Zakraoui and Sami Fattouch and Habib Karoui and Khadija Essafi-Benkhadir},
  booktitle={Cancer Cell International},
  year={2015}
}
Development of alternative cancer-specific drugs would be of paramount importance to overcome toxicity toward normal tissues and tumor resistance. Here, we investigated the potential anti-tumoral effect of peel (Peph) and pulp polyphenolic extracts from the Tunisian quince Cydonia oblonga Miller on both no-tumorigenic cells NIH 3T3 Fibroblasts and HEK 293 cells and human colon adenocarcinoma LS174 cells. Cell proliferation and cytotoxicity were measured with MTT and LDH assays respectively… CONTINUE READING

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