Quiescent lymphocytes express intracellular transferrin receptors.

  title={Quiescent lymphocytes express intracellular transferrin receptors.},
  author={J. E. Weiel and Thomas A Hamilton},
  journal={Biochemical and biophysical research communications},
  volume={119 2},
Both quiescent and concanavalin A stimulated murine splenic lymphocytes were examined for the expression of surface and intracellular binding sites for the serum glycoprotein transferrin. Transferrin binding activity was observed on the surface of mitogen stimulated cells only. When soluble detergent extracts of both populations were studied, quiescent lymphocytes were shown to contain a significant pool of non-surface exposed, intracellular receptors which was approximately 20% of the total… CONTINUE READING