Questioning the depolarizing effects of GABA during early brain development.
@article{Khakhalin2011QuestioningTD, title={Questioning the depolarizing effects of GABA during early brain development.}, author={Arseny S Khakhalin}, journal={Journal of neurophysiology}, year={2011}, volume={106 3}, pages={ 1065-7 } }
During early brain development, γ-aminobutyric acid (GABA), the main inhibitory neurotransmitter in the adult brain, has been thought to be an important source of excitatory neurotransmission. This view, however, was recently challenged by a series of studies that claim that the excitatory effect of GABA is due to non-physiological in vitro experimental conditions. In this article, we aim to summarize results that support and challenge the traditional point of view, and indicate some strong and…
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