• DOI:10.1152/jn.00293.2011
Corpus ID: 13966338

Questioning the depolarizing effects of GABA during early brain development.

@article{Khakhalin2011QuestioningTD,
  title={Questioning the depolarizing effects of GABA during early brain development.},
  author={Arseny S Khakhalin},
  journal={Journal of neurophysiology},
  year={2011},
  volume={106 3},
  pages={
          1065-7
        }
}

Arseny S Khakhalin

Published 2011

Psychology, Medicine

Journal of neurophysiology

During early brain development, γ-aminobutyric acid (GABA), the main inhibitory neurotransmitter in the adult brain, has been thought to be an important source of excitatory neurotransmission. This view, however, was recently challenged by a series of studies that claim that the excitatory effect of GABA is due to non-physiological in vitro experimental conditions. In this article, we aim to summarize results that support and challenge the traditional point of view, and indicate some strong and… CONTINUE READING

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