Questioning the depolarizing effects of GABA during early brain development.

  title={Questioning the depolarizing effects of GABA during early brain development.},
  author={Arseny S Khakhalin},
  journal={Journal of neurophysiology},
  volume={106 3},
  • Arseny S Khakhalin
  • Published 2011
  • Psychology, Medicine
  • Journal of neurophysiology
  • During early brain development, γ-aminobutyric acid (GABA), the main inhibitory neurotransmitter in the adult brain, has been thought to be an important source of excitatory neurotransmission. This view, however, was recently challenged by a series of studies that claim that the excitatory effect of GABA is due to non-physiological in vitro experimental conditions. In this article, we aim to summarize results that support and challenge the traditional point of view, and indicate some strong and… CONTINUE READING
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