Questionable role of leukotriene B4 in monosodium urate (MSU)-induced synovitis in the dog.

Abstract

Monosodium urate (MSU)-induced synovitis in the dog's stifle (knee joint) is similar to an acute gouty attack in man in which a loss of function of the joint correlates with massive influx of neutrophils and the release of an assortment of inflammatory mediators (e.g. histamine, bradykinin, lysosomal enzymes, complement and eicosanoids) into the synovial… (More)

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@article{Carlson1986QuestionableRO, title={Questionable role of leukotriene B4 in monosodium urate (MSU)-induced synovitis in the dog.}, author={Rolf Carlson and J. Chang and Louis J. Datko and A. J. Lewis}, journal={Prostaglandins}, year={1986}, volume={32 4}, pages={579-85} }