Quest for genes and mechanisms linking the human chromosome 9p21.3 locus to cardiovascular disease.

@article{Hamsten2012QuestFG,
  title={Quest for genes and mechanisms linking the human chromosome 9p21.3 locus to cardiovascular disease.},
  author={Anders Hamsten and Per Eriksson},
  journal={Circulation},
  year={2012},
  volume={126 15},
  pages={1815-7}
}
In the past several years, advances in molecular genetics have been adopted as tools to dissect the cause and pathophysiology of common complex diseases and their associated risk factors in a hypothesis-free approach, using the genome-wide association study design and high-density, single nucleotide polymorphism (SNP) genotyping arrays. Starting in 2007 with the discovery of the chromosome 9p21.3 (Chr9p21.3) locus (see recent review),1 major progress has been made in terms of identification of… CONTINUE READING
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