Quercetin relaxes guinea pig gallbladder strips.

@article{Kline2016QuercetinRG,
  title={Quercetin relaxes guinea pig gallbladder strips.},
  author={Loren W. Kline and Edward Karpinski},
  journal={Nutrition research},
  year={2016},
  volume={36 10},
  pages={
          1098-1104
        }
}

The Flavone Luteolin, an Endocrine Disruptor, Relaxed Male Guinea Pig Gallbladder Strips

  • L. Kline
  • Biology, Medicine
    Gastroenterology research
  • 2019
TLDR
In this study, luteolin relaxed cholecystokinin- or KCl-induced tension by blocking extracellular Ca2+ entry as well as intracellular Ca 2+ release and the actions of PKA are also involved in mediating the lutenolin effect.

Relaxant Activities of Extracts from Uvaria rufa Blume and Caesalpinia sappan L. on Excised Rat’s Prostate Strips

TLDR
The ethyl acetate from the stems of U. rufa was the most potent in relaxing the prostate smooth muscles, and it may be useful to relieve the urological symptoms caused by benign prostatic hyperplasia (BPH).

2-aminoethyldiphenyl borinate: a multitarget compound with potential as a drug precursor.

TLDR
The molecular pharmacology of 2-APB supports both its potential to act as a drug and the desirable inclusion of its moieties in new drug development.

References

SHOWING 1-10 OF 35 REFERENCES

Effects of quercetin and rutin on vascular preparations

TLDR
The mechanical and electrophysiological properties of quercetin and its rutoside, rutin, are investigated in an attempt to clarify how Ca2+ channel activation might be related to the myorelaxing activity.

Vasodilator effects of quercetin in isolated rat vascular smooth muscle.

Progesterone inhibits gallbladder motility through multiple signaling pathways

17β-Estradiol relaxes cholecystokinin- and KCl-induced tension in male guinea pig gallbladder strips

Gastric relaxation induced by apigenin and quercetin: analysis of the mechanism of action.

Calcitonin gene-related peptide: an inhibitor of guinea pig gallbladder contraction.

TLDR
Calcitonin gene-related peptide (CGRP) relaxes vascular and intestinal smooth muscle and may in part act directly on the gallbladder smooth muscle to inhibit contraction.

Inhibition of Guinea Pig Intestinal Peristalsis by the Flavonoids Quercetin, Naringenin, Apigenin and Genistein

TLDR
Naringenin and quercetin inhibit peristalsis by facilitating inhibitory enteric pathways, whereas apigenin and genistein interfere with muscle excitation or excitation-contraction coupling.