Quercetin exerts a neuroprotective effect through inhibition of the iNOS/NO system and pro-inflammation gene expression in PC12 cells and in zebrafish.

@article{Zhang2011QuercetinEA,
  title={Quercetin exerts a neuroprotective effect through inhibition of the iNOS/NO system and pro-inflammation gene expression in PC12 cells and in zebrafish.},
  author={Zaijun Zhang and Lorita Chi Veng Cheang and Mei Wei Wang and Simon Ming-yuen Lee},
  journal={International journal of molecular medicine},
  year={2011},
  volume={27 2},
  pages={195-203}
}
Flavonoids have been reported to be potent antioxidants and beneficial in the treatment of oxidative stress-related diseases. Quercetin, a major flavonoid naturally occurring in plants, deserves attention because of its beneficial effects observed in various in vitro and in vivo neural damage models; however, the actions of quercetin are paradoxical. In an effort to confirm the neuroprotective effect of quercetin and to elucidate its mechanism of action, the neuroprotective effects of quercetin… CONTINUE READING