Quercetin attenuates di-(2-ethylhexyl) phthalate-induced testicular toxicity in adult rats.

@article{AbdEllah2016QuercetinAD,
  title={Quercetin attenuates di-(2-ethylhexyl) phthalate-induced testicular toxicity in adult rats.},
  author={Mohamed Fahmy Abd-Ellah and Hamdy A A Aly and H A M Mokhlis and Abdel-Aziz H. Abdel-Aziz},
  journal={Human & experimental toxicology},
  year={2016},
  volume={35 3},
  pages={232-43}
}
The aim of the present study was to investigate the potential oxidative damage of di-(2-ethylhexyl) phthalate (DEHP) in the rat testis and to further elucidate the potential modulatory effect of quercetin. DEHP was diluted in corn oil and given to rats by oral gavage at doses 0, 300, 600, and 900 mg/kg/day (groups I, III, IV, or V, respectively) for 15 consecutive days. Group VI was pretreated with quercetin (90 mg/kg), 24 h before starting the experiment and then treated with DEHP (900 mg/kg… CONTINUE READING