Quercetin and the growth of leukemic progenitors.

@article{Larocca1996QuercetinAT,
  title={Quercetin and the growth of leukemic progenitors.},
  author={Luigi Maria Larocca and Luciana Teofili and Nicola Giuseppe Maggiano and Mauro Piantelli and Franco Oreste Ranelletti and Giuseppe Leone},
  journal={Leukemia & lymphoma},
  year={1996},
  volume={23 1-2},
  pages={
          49-53
        }
}
The bioflavonoid quercetin (3, 3', 4', 5-7-pentahydroxyflavone) inhibits in a dose-dependent manner the in vitro growth of acute leukemias and enhances the anti-proliferative activity of cytosine arabinoside. Quercetin exerts a blocking action of cell transition from the G0/G1 to the S phase of the cell cycle. Acute myeloid leukemias (AML)-M3,-M4 and -M5, and acute lymphoid leukemias (ALL) were more sensitive to quercetin than AML-M1 and -M2 subtypes. The sensitivity of leukemic progenitors to… CONTINUE READING
BETA

Similar Papers

Citations

Publications citing this paper.
SHOWING 1-8 OF 8 CITATIONS