Quercetin and rutin as potential agents antifungal against Cryptococcus spp.
@article{Oliveira2016QuercetinAR, title={Quercetin and rutin as potential agents antifungal against Cryptococcus spp.}, author={V M Oliveira and Emerson Carraro and Marcos Ereno Auler and Najeh Maissar Khalil}, journal={Brazilian journal of biology = Revista brasleira de biologia}, year={2016}, volume={76 4}, pages={ 1029-1034 } }
Amphotericin B is a fungicidal substance that is treatment of choice for most systemic fungal infections affecting as cryptococcosis the immunocompromised patients. However, severe side effects have limited the utility of this drug. The aim of this study was to evaluate the antifungal effect of the combination of amphotericin B with quercetin or rutin and as a protective of citotoxic effect. The antifungal activity to amphotericin B, quercetin and rutin alone and in combination was determined…
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