Quercetin ameliorates methotrexate-induced renal damage, apoptosis and oxidative stress in rats

@article{Erboa2015QuercetinAM,
  title={Quercetin ameliorates methotrexate-induced renal damage, apoptosis and oxidative stress in rats},
  author={Mustafa Erboğa and Cevat Aktaş and Zeynep Fidanol Erboğa and Yeliz Bozdemir Donmez and Ahmet Gurel},
  journal={Renal Failure},
  year={2015},
  volume={37},
  pages={1492 - 1497}
}
Abstract Background: In the present study, the protective and therapeutic effects of quercetin (QE) on renal injury induced by methotrexate (MTX) have been examined. Materials and methods: A total of 24 male rats were divided into the following three groups: control group, MTX group, and MTX + QE group. Rats in MTX group received 20 mg/kg of single dose of MTX, while those in MTX + QE group received 20 mg/kg of single dose MTX, in addition to 15 mg/kg of QE administered 30 min prior to MTX and… Expand
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  • Journal of the Institute of Science and Technology
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