Quercetin-3-O-β-D-glucuronide isolated from Polygonum aviculare inhibits cellular senescence in human primary cells.

@article{Yang2014Quercetin3ODglucuronideIF,
  title={Quercetin-3-O-β-D-glucuronide isolated from Polygonum aviculare inhibits cellular senescence in human primary cells.},
  author={Hyo Hyun Yang and Kyoung Hwangbo and Ming Shan Zheng and Jung Hee Cho and J O Son and Hwa Young Kim and Suk Hwan Baek and Hyung Chul Choi and So Young Park and J W Kim},
  journal={Archives of pharmacal research},
  year={2014},
  volume={37 9},
  pages={1219-33}
}
Cellular senescence is known to contribute to tissue aging, a variety of age-related diseases, tissue regeneration, and cancer. Therefore, aging intervention might be useful for prevention of aging as well as age-related disease. In this study, we investigated compounds from Polygonum aviculare to determine if they inhibited cellular senescence in human primary cells, human dermal fibroblasts (HDFs) and human umbilical vein endothelial cells (HUVECs). Ten compounds from P. aviculare were… CONTINUE READING