Quaternary structure of Artemia haemoglobin II: analysis of T and C polymer alignment and interpolymer interface

@article{Chyou2006QuaternarySO,
  title={Quaternary structure of Artemia haemoglobin II: analysis of T and C polymer alignment and interpolymer interface},
  author={David T Chyou and Vincent L Rawle and Clive NA Trotman},
  journal={BMC Structural Biology},
  year={2006},
  volume={7},
  pages={26 - 26}
}
The brine shrimp Artemia expresses four different types of haemoglobin subunits namely C1, C2, T1 and T2. Two of these four subunits dimerize in different combinations to produce the three isoforms of the heterodimeric Artemia haemoglobin: HbI (C1 and C2), HbII (C1 and T2) and HbIII (T1 and T2). Previous biochemical, biophysical and computational analyses demonstrate that the T and C polymers are rings of nine concatenated globin domains, which are covalently joined by interdomain linkers. Two… CONTINUE READING