Quantum-dot/dopamine bioconjugates function as redox coupled assemblies for in vitro and intracellular pH sensing.

@article{Medintz2010QuantumdotdopamineBF,
  title={Quantum-dot/dopamine bioconjugates function as redox coupled assemblies for in vitro and intracellular pH sensing.},
  author={Igor L. Medintz and Michael H. Stewart and Scott A. Trammell and Kimihiro Susumu and James B. Delehanty and Bing C Mei and Joseph. S. Melinger and Juan B. Blanco-Canosa and Philip E. Dawson and Hedi Mattoussi},
  journal={Nature materials},
  year={2010},
  volume={9 8},
  pages={676-84}
}
The use of semiconductor quantum dots (QDs) for bioimaging and sensing has progressively matured over the past decade. QDs are highly sensitive to charge-transfer processes, which can alter their optical properties. Here, we demonstrate that QD-dopamine-peptide bioconjugates can function as charge-transfer coupled pH sensors. Dopamine is normally characterized by two intrinsic redox properties: a Nernstian dependence of formal potential on pH and oxidation of hydroquinone to quinone by O(2) at… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 57 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 71 references

Influence of surface charge on sensing and colloidal properties

Zhang, F. et al. Ion, pH sensing with colloidal nanoparticles
ChemPhysChem 11, 730–735 • 2010

Predicted versus experimental results

Prasuhn, D. E. et al. Polyvalent display, packing of peptides, proteins on semiconductor quantum dots
Small 6, 555–564 • 2010

Applications to probe NAD(+)-dependent enzymes and to sense the RDX explosive

R. Freeman, Willner, I. NADNADH-sensitive quantum dots
Nano Lett. 9, 322–326 • 2009

Effects of ligand coordination number and surface curvature on the stability of gold nanoparticles in aqueous solutions

Mei, C B.
Langmuir 25, • 2009

Monitoring of enzymatic proteolysis on a electroluminescent-CCD microchip platform using quantum dot–peptide substrates

Sapsford, E K.
Sens. Actuat. B 139, • 2009

Similar Papers

Loading similar papers…