Quantitatively and qualitatively different cellular processes are engaged in CA1 during the consolidation and reconsolidation of contextual fear memory.

@article{Barnes2012QuantitativelyAQ,
  title={Quantitatively and qualitatively different cellular processes are engaged in CA1 during the consolidation and reconsolidation of contextual fear memory.},
  author={Philip Barnes and Anne Kirtley and Kerrie L. Thomas},
  journal={Hippocampus},
  year={2012},
  volume={22 2},
  pages={149-71}
}
Whether the consolidation and reconsolidation long-term memory relies on qualitatively different molecular and cellular processes is controversial. Using a novel experimental strategy of combining intrahippocampal antisense oligodeoxynucleotides targeting BDNF or zif268 to the block consolidation or reconsolidation of contextual fear memory respectively, and Affymetrix microarray technology, we identified a comprehensive list of nonoverlapping candidate genes regulated in CA1 during the initial… CONTINUE READING
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