Quantitative urinary proteomics using stable isotope labelling by peptide dimethylation in patients with prostate cancer.

@article{Li2015QuantitativeUP,
  title={Quantitative urinary proteomics using stable isotope labelling by peptide dimethylation in patients with prostate cancer.},
  author={Chunhui Li and Tuo Zang and Karolina Wr{\'o}bel and Jeffrey T-J Huang and Ghulam Nabi},
  journal={Analytical and bioanalytical chemistry},
  year={2015},
  volume={407 12},
  pages={3393-404}
}
Prostate cancer (PCa) is the most commonly diagnosed malignancy in men. The current prevalent diagnosis method, prostate-specific antigen (PSA) screening test, has low sensitivity, specificity and is poor at predicting the grade of disease. Thus, new biomarkers are urgently needed to improve the PCa diagnosis and staging for the management of patients. The aim of this study is to investigate the first voided urinary sample after massage for biomarker discovery for PCa. In this work, untargeted… CONTINUE READING

Similar Papers

Loading similar papers…