Quantitative und qualitative Untersuchungen über den Sympathicusstoff

@article{Loewi2005QuantitativeUQ,
  title={Quantitative und qualitative Untersuchungen {\"u}ber den Sympathicusstoff},
  author={Otto Loewi},
  journal={Pfl{\"u}ger's Archiv f{\"u}r die gesamte Physiologie des Menschen und der Tiere},
  year={2005},
  volume={237},
  pages={504-514}
}
  • O. Loewi
  • Published 1 December 1936
  • Chemistry
  • Pflüger's Archiv für die gesamte Physiologie des Menschen und der Tiere
History of catecholamine research.
  • K. Starke
  • Medicine
    Chemical immunology and allergy
  • 2014
The prominence of catecholamines and their congeners in allergic diseases rests chiefly on their use in asthma and acute hypersensitivity reactions, such as anaphylaxis. They act in these indications
Functional neuroanatomy of the central noradrenergic system
  • E. Szabadi
  • Biology, Medicine
    Journal of psychopharmacology
  • 2013
TLDR
The central noradrenergic neurone, like the peripheral sympathetic neur one, is characterized by a diffusely arborizing terminal axonal network, of which the locus coeruleus (LC) is the most prominent.
Adrenaline and Noradrenaline: Partners and Actors in the Same Play"
Vera Marisa Costa1, Felix Carvalho1, Maria Lourdes Bastos1, Rui Albuquerque Carvalho2, Marcia Carvalho1,3 and Fernando Remiao1 1REQUIMTE Toxicology Laboratory, Department of Biologic Sciences,
Cellular Aspects of Catecholaminergic Neurons
TLDR
The sections in this article are: Identification of the Sympathetic Transmitter, Quantitative Aspects of Transmitter Distribution, Enzymes Involved in Catecholamine Metabolism, and Life Cycle of Noradrenergic Synaptic Vesicles.
Role of catecholamines and reactive oxygen species in the mechanism of oxidative stress-induced heart disease:in vitro studies using fresly isolated rat cardiomyocytes
TLDR
The catecholamines and the heart: physiological and clinical signals, physiology and pharmacology, and the role of adrenergic receptors and receptors in the heart are studied.
Catecholamines, cardiac natriuretic peptides and chromogranin A: evolution and physiopathology of a ‘whip-brake’ system of the endocrine heart
TLDR
The actions of CA, NP and CgA, it is argued, may be viewed as a hallmark of the cardiac capacity to organize ‘whip-brake’ connection-integration processes in spatio-temporal networks.
The Endocrine–Paracrine Control of the Cardiovascular System
TLDR
This chapter comparatively summarizes the information available on the hearts of cold-blooded vertebrates with regard to these major endocrine and paracrine agents, although many serious gaps are particularly evident in amphibians and reptiles due to discontinuous information being available.
Catestatin (chromogranin A344-364) is a novel cardiosuppressive agent: inhibition of isoproterenol and endothelin signaling in the frog heart.
TLDR
The cardiotropic actions of Cts, including the beta-adrenergic and ET-1 antagonistic effects, support a novel role of this peptide as an autocrine-paracrine modulator of cardiac function, particularly when the stressed heart becomes a preferential target of both adrenergic andET-1 stimuli.
is a novel cardiosuppressive agent : inhibition of isoproterenol and endothelin signaling in the frog heart 1
Corresponding Author: *S. K. Mahata, Department of Medicine, University of California & VA San Diego Healthcare System, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0838 USA. Tel: (858)552-8585,
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    Pflüger's Archiv für die gesamte Physiologie des Menschen und der Tiere
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Zusammenfassung1.Durch die Übertragung von Blut, das während einer Reizung der Nn. vagi aus dem Sinus coronarius des Herzens eines Spendertieres entnommen und dem linken Vorhofe des Herzens eines
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    Pflüger's Archiv für die gesamte Physiologie des Menschen und der Tiere
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ZusammenfassungErgebnisse1.Im nichtgereizten Froschherzen ist der Gehalt an Vagusstoff in Vorhof und Ventrikel auf die Gewichtseinheit berechnet ganz gleich. Nach Vagusreizung steigt der Gehalt in
Über humorale Übertragbarkeit der Herznervenwirkung
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    Pflüger's Archiv für die gesamte Physiologie des Menschen und der Tiere
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ZusammenfassungDer Inhalt von Vagusreizperioden von einem Herzen, das vorgängig soweit atropinisiert wurde, daβ jeder mechanische Vagusreizerfolg entfällt, fuhrt bei einem vorgängig nicht
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The results of experiments hitherto made to decide the question have been regarded as favouring a mechanism in which the transmitter is newly formed in response to the nerve impulse, rather than one in which it is released from an inactive depot.
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IN attempting to analyse the phenomenon, that during the stimulation of the vagus to the isolated frog's heart a vagomimetic substance appears in the perfusion fluid, Witanowski [1925], Plattner
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The humoral interpretation would seem to offer a means of recording the occurrence of the phenomenon with the apparent absence of a direct sympathetic supply to the muscle tissue; for the only sympathetic nerves in muscle whose existence is beyond dispute are those its blood vessels.