Quantitative ultrastructural analysis of hippocampal excitatory synapses.
@article{Schikorski1997QuantitativeUA,
title={Quantitative ultrastructural analysis of hippocampal excitatory synapses.},
author={Th. Schikorski and Charles F. Stevens},
journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
year={1997},
volume={17 15},
pages={
5858-67
}
}
From three-dimensional reconstructions of CA1 excitatory synapses in the rodent hippocampus and in culture, we have estimated statistical distributions of active zone and postsynaptic density (PSD) sizes (average area approximately 0.04 micron2), the number of active zones per bouton (usually one), the number of docked vesicles per active zone (approximately 10), and the total number of vesicles per bouton (approximately 200), and we have determined relationships between these quantities, all… CONTINUE READING