Quantitative trait locus mapping for acute functional tolerance to ethanol in the L x S recombinant inbred panel.

@article{Bennett2007QuantitativeTL,
  title={Quantitative trait locus mapping for acute functional tolerance to ethanol in the L x S recombinant inbred panel.},
  author={Beth Bennett and Chris Downing and Phyllis J. Carosone-Link and Heather Ponicsan and Cathy Ruf and Thomas Johnson},
  journal={Alcoholism, clinical and experimental research},
  year={2007},
  volume={31 2},
  pages={200-8}
}
BACKGROUND Acute functional tolerance (AFT) develops shortly after ethanol administration, and is determined as the change in brain or blood ethanol concentration (BEC) measured at 2 behavioral or physiological endpoints. Acute functional tolerance studies in some rodent strains support a long-held hypothesis that more sensitive strains develop more within-session tolerance. We used the new, 74-strain L x S recombinant inbred (RI) panel, developed from inbred long-sleep (ILS) and inbred short… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 16 extracted citations

Genomic insights into acute alcohol tolerance.

The Journal of pharmacology and experimental therapeutics • 2008
View 2 Excerpts
Highly Influenced

Genetic Research

Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism • 2010
View 1 Excerpt

Similar Papers

Loading similar papers…