Quantitative trait loci for ethanol sensitivity in the LS X SS recombinant inbred strains: Interval mapping

@article{Markel1996QuantitativeTL,
  title={Quantitative trait loci for ethanol sensitivity in the LS X SS recombinant inbred strains: Interval mapping},
  author={Paul D. Markel and David W. Fulker and Beth Bennett and Robin P. Corley and John C. DeFries and V. Gene Erwin and Thomas E. Johnson},
  journal={Behavior Genetics},
  year={1996},
  volume={26},
  pages={447-458}
}
We are mapping the genes (quantitative trait loci or QTLs) that are responsible for individual differences in ethanol sensitivity, measured as the duration of loss of righting reflex (LORR) and blood ethanol concentrations upon recovery of the righting reflex (BEC). The Long-Sleep (LS) and Short-Sleep (SS) selected lines of mice manifest an 18-fold difference in LORR and serve as a rodent model for ethanol sensitivity. The LS x SS recombinant inbred (RI) series, developed from LS and SS lines… CONTINUE READING

Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 21 CITATIONS

Single-gene influences on brain and behavior.

  • Annual review of psychology
  • 1999
VIEW 1 EXCERPT
CITES BACKGROUND
HIGHLY INFLUENCED

High genetic susceptibility to ethanol withdrawal predicts low ethanol consumption

Pamela Metten, Tamara J. Phillips, +5 authors John K. Belknap
  • Mammalian Genome
  • 1998
VIEW 1 EXCERPT
CITES BACKGROUND
HIGHLY INFLUENCED

A genomic imprinting test for ordinal traits in pedigree data.

  • Genetic epidemiology
  • 2008
VIEW 1 EXCERPT
CITES BACKGROUND