Quantitative trait loci affecting dengue midgut infection barriers in an advanced intercross line of Aedes aegypti.

@article{GomezMachorro2004QuantitativeTL,
  title={Quantitative trait loci affecting dengue midgut infection barriers in an advanced intercross line of Aedes aegypti.},
  author={Consuelo Gomez-Machorro and Kristine Bennett and M del Lourdes Munoz and William C. Black},
  journal={Insect molecular biology},
  year={2004},
  volume={13 6},
  pages={637-48}
}
Quantitative trait loci (QTL) affecting the ability of the Aedes aegypti midgut to become infected with Dengue 2 virus (DEN2) were mapped in the F5 generation of an advanced intercross line (AIL). A strain of Ae. aegypti previously selected for DEN2 susceptibility was crossed to a new strain selected for refractoriness to midgut infection. In P1 and F1 parents and 147 F5 offspring, genotypes at forty-four cDNA loci were analysed. A new sex linked QTL and a second QTL on chromosome II with… CONTINUE READING
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