Quantitative systems-level determinants of drug targets

  title={Quantitative systems-level determinants of drug targets},
  author={Lixia Yao and Andrey Rzhetsky},
  journal={BMC Bioinformatics},
Background Modern drug discovery tends to understand disease processes at the molecular level and then determine optimal molecular targets for drug intervention. Inferences have made from all available drug targets, such as how many drug targets there are, or how many novel drug targets could be potentially found in the human genome, to what functional families these proteins belong, and what structural properties make them bind to small molecules tightly and specifically. But all these are… CONTINUE READING