Quantitative surface-enhanced Raman spectroscopy of single bases in oligodeoxynucleotides.

Abstract

To address the question of whether the SERS signals of ss-DNA are simply combinations of the signals from the individual bases that comprise the sequence, SERS spectra of unmodified ss-DNA sequences were obtained using a hydroxylamine-reduced Ag colloid aggregated with MgSO4. Initially, synthetic oligodeoxynucleotides with systematic structural variations… (More)
DOI: 10.1039/c7fd00134g

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