Quantitative structure-activity relationships in cytokinin agonistic and antagonistic pyrido[2,3-d]pyrimidine derivatives: insights into receptor topology.

@article{Iwamura1985QuantitativeSR,
  title={Quantitative structure-activity relationships in cytokinin agonistic and antagonistic pyrido[2,3-d]pyrimidine derivatives: insights into receptor topology.},
  author={Hajime Iwamura and Shigeru Murakami and Koichi Koshimizu and Seijiro Matsubara},
  journal={Journal of medicinal chemistry},
  year={1985},
  volume={28 5},
  pages={577-83}
}
2-(Methylthio)pyrido[2,3-d]pyrimidines having various alkylamino and anilino substituents at the 4-position were prepared and tested for their cytokinin agonistic and antagonistic activities by the tobacco callus bioassay. The alkyl series of compounds showed anticytokinin activity, whereas the anilino derivatives exhibited both cytokinin and anticytokinin… CONTINUE READING