Quantitative structure-activity relationships for the toxicity of chlorophenols to mammalian submitochondrial particles.

Abstract

The toxicity of a series of chlorophenols, determined by a short-term in vitro assay utilizing mammalian submitochondrial particles, was related to the physicochemical and structural properties of these compounds. Quantitative Structure-Activity Relationships were defined by correlating EC50 values with six molecular descriptors, chosen to represent… (More)

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@article{Argese1999QuantitativeSR, title={Quantitative structure-activity relationships for the toxicity of chlorophenols to mammalian submitochondrial particles.}, author={Emanuele Argese and Cinzia Bettiol and G Giurin and Paola Miana}, journal={Chemosphere}, year={1999}, volume={38 10}, pages={2281-92} }