Quantitative structure-activity relationships and mixture toxicity studies of chloro- and alkylanilines at an acute lethal toxicity level to the guppy (Poecilia reticulata).

Quantitative structure-activity relationships (QSARs) were calculated for the acute lethal toxicities (14-day LC50) to the guppy (Poecilia reticulata) of anilines, with several hydrophobicity characteristics and the Hammett sigma constant as parameters. Calculated and experimental Poct values and II constants were used as hydrophobicity characteristics… (More)