Quantitative relationships of intravascular tumor cells, tumor vessels, and pulmonary metastases following tumor implantation.

@article{Liotta1974QuantitativeRO,
  title={Quantitative relationships of intravascular tumor cells, tumor vessels, and pulmonary metastases following tumor implantation.},
  author={Lance A. Liotta and Jerome I Kleinerman and Gerald M. Saidel},
  journal={Cancer research},
  year={1974},
  volume={34 5},
  pages={997-1004}
}
An experimental model has been developed to quantify some of the major processes initiated by tumor transplanta tion and culminating in pulmonary métastases.The T241 fibrosarcoma, chosen because of its high hematogenous metastatic propensity and reproducible biological behavior, is transplanted into the femoral region of the C57BL mouse. Experiments are performed at specified times after trans plantation to determine the dynamics of tumor growth, density, and size distribution of perfused… CONTINUE READING

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