Quantitative relationship between synonymous codon usage bias and GC composition across unicellular genomes

@article{Wan2004QuantitativeRB,
  title={Quantitative relationship between synonymous codon usage bias and GC composition across unicellular genomes},
  author={Xiu-Feng Wan and Dong Xu and Andris Kleinhofs and Jizhong Zhou},
  journal={BMC Evolutionary Biology},
  year={2004},
  volume={4},
  pages={19 - 19}
}
Codon usage bias has been widely reported to correlate with GC composition. However, the quantitative relationship between codon usage bias and GC composition across species has not been reported. Based on an informatics method (SCUO) we developed previously using Shannon informational theory and maximum entropy theory, we investigated the quantitative relationship between codon usage bias and GC composition. The regression based on 70 bacterial and 16 archaeal genomes showed that in bacteria… CONTINUE READING