Quantitative real-time RT-PCR analysis of eight novel estrogen-regulated genes in breast cancer.

@article{Sorbello2003QuantitativeRR,
  title={Quantitative real-time RT-PCR analysis of eight novel estrogen-regulated genes in breast cancer.},
  author={Valentina Sorbello and Luca Fuso and Christian Sfiligoi and Claudio Scafoglio and Riccardo Ponzone and Nicoletta Biglia and Alessandro Weisz and Piero Sismondi and Michele De Bortoli},
  journal={The International journal of biological markers},
  year={2003},
  volume={18 2},
  pages={123-9}
}
BACKGROUND Biological markers capable of predicting the risk of recurrence and the response to treatment in breast cancer are eagerly awaited. Estrogen and progesterone receptors (ER, PgR) in tumor cells mark cancers that are more likely to respond to endocrine treatment, but up to 40% of such patients do not respond. Here, the expression of a group of estrogen-regulated genes, previously identified by microarray analysis of in vitro models, was measured in breast tumors and possible… CONTINUE READING
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